Shirkadda Shiinaha ee jumlada ah ee Tayada ugu Fiican Qiimaha ugu Hooseeya ee Kaabista Cuntada Beta Nicotinamide Mononucleotide Nmn CAS 1094-61-7
Waxaan sidoo kale ku takhasusnay hagaajinta maaraynta waxyaabaha iyo habka QC si aan u sii haysanno faa'iidada ugu weyn ee ganacsiga yaryar ee aadka u tartan badan ee Shiinaha ee jumlada ah ee Tayada ugu Fiican Qiimaha ugu Yar ee Kaabista Cuntada Beta Nicotinamide Mononucleotide Nmn CAS 1094-61-7, Waxaan rajeyneynaa inaan hubinno is-dhexgal ganacsi oo aad u badan oo lala yeesho macaamiisha adduunka oo dhan.
Waxaan sidoo kale ku takhasusnay horumarinta maaraynta waxyaabaha iyo habka QC si aan u sii haysanno faa'iidada ugu weyn ee ganacsiga yar yar ee aadka u tartan badan.Shiinaha Nicotinamide Mononucleotide iyo NrHadda, si xirfad leh ayaan macaamiisha ugu siinaa alaabtayada ugu muhiimsan. Ganacsigeennu ma aha oo kaliya "iibso" iyo "iibso", laakiin sidoo kale waxaan diiradda saarnaa wax badan. Waxaan higsaneynaa inaan noqono alaab-qeybiyahaaga daacadda ah iyo iskaashiga muddada dheer ee Shiinaha. Hadda, waxaan rajeyneynaa inaan saaxiibo kula noqono.
Dhawaan, waxaa jira war wanaagsan oo ku saabsan NMN - ka dib markii ay si adag u eegeen guddiga xirfadeed ee hay'adda awoodda u leh Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA), agabka cayriin ee NMN ee Shangke Biopharmaceutical (Shanghai) Co., Ltd. (oo hadda loogu yeero "Shangke Bio") ayaa ansixiyay oggolaanshaha FDA NDI ee Mareykanka waxayna xaqiijineysaa in agabka cayriin ee NMN si rasmi ah loogu isticmaali karo wax soo saarka, iibinta iyo kor u qaadista kaabayaasha cuntada ee Mareykanka, waxaana laga heli karaa bogga rasmiga ah ee FDA oo ah agab cayriin oo cusub oo dheeri ah oo cunto ah, lambar 1247.
FDA NDI waa nidaamka shahaadada ugu muhiimsan suuqa Mareykanka. Helitaanka shahaadadan macnaheedu maahan oo keliya in badbaadada iyo tayada alaabada Shangke Bio si weyn loo aqoonsaday, laakiin sidoo kale waxay gacan ka geysaneysaa horumarinta joogtada ah ee heerka warshadaha NMN mustaqbalka fog.
| Magaca Kiimikada | β-Nicotinamide Mononucleotide |
| Erayo isku mid ah | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5′-FOSBAHEED |
| Lambarka CAS | 1094-61-7 |
| Miisaanka Molekulerka | 334.22 |
| Qaacidda Molekuleerigga | C11H15N2O8P |
| EINECS wuxuu leeyahay: | 214-136-5 |
| Barta dhalaalaysa | 166 °C(Diseembar) |
| heerkulka kaydinta. | -20°C |
| milmida | DMSO (Waxoogaa yar, Kulayl leh), Methanol (Waxoogaa yar), Biyo (Waxoogaa yar) |
| qaab | Adag |
| midab | Cadaan ilaa Jaalle |
| Merck | 13,6697 |
| BRN | 3570187 |
| Xasilloonida: | Aad u Hygroscopic ah |
| InChiKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Shayga Tijaabada | Tilmaamaha |
| Muuqaalka | Budada kristalinta cad ilaa caddaan ah |
| Waxyaabaha soodhiyamku ka kooban yahay | ≤1% |
| Qiimaha pH (100mg/ml) | 2.0~4.0 |
| Daahirnimo | ≥99.0% |
| Biyaha ku jira | ≤1% |
| Biraha culus | <10ppm |
| Arsenik | <0.5ppm |
| Hoggaanka | <0.5ppm |
| Meerkuriga | <0.1ppm |
| Cadmium | <0.5ppm |
| Hadhaaga dareeraha ah | Etanool ≤1000ppm |
| Wadarta Tirada Microbial-ka Hawada Sare | <750cfu/g |
| Khamiirka iyo Caaryada | <25cfu/g |
| Wadarta coliform | ≤0.92MPN/g |
| E. Coli | Taban |
| Salmonella | Taban |
| Staph. Aureus | Taban |
| Baaritaan (oo ku salaysan biyo la'aan) | ≥99.0% |
| Heerka kala-goynta | ≥95% |
| Cufnaanta badan | Ka warbixi macluumaadka |
Xirmada:Dhalo, bacda aluminium-ka, 25kg/Durbaan Kaarboor, ama sida waafaqsan shuruudaha macaamiisha.
Xaaladda Kaydinta:Ku hay weelal adag oo iftiin u adkaysta, si aad u kaydiso muddo dheer, ku hay heerkul ah 2-8°C ama ka hooseeya.
Nicotinamide Mononucleotide (NMN) waa nooc cusub oo fiitamiin B3 ah kaas oo ah horudhac 1 tallaabo ah oo loo maro NAD+ (Nicotinamide Adenine Dinucleotide). NMN waa soo-celinta unugyada NAD+ ee ugu horreysa ee la xaqiijiyay inay waxtar u leedahay soo celinta unugyada gudaha jirka.
Nicotinamide Adenine Dinucleotide (NAD) waa mid ka mid ah molecules-ka ugu muhiimsan uguna xiisaha badan jirka. Waxaa looga baahan yahay in ka badan 500 oo falgal enzymatic ah waxayna door muhiim ah ka ciyaartaa nidaaminta ku dhawaad dhammaan hababka bayoolojiga ee waaweyn (Ansari iyo Raghava, 2010). Waxa ugu muhiimsan, waxay noo ogolaan kartaa inaan ku noolaano nolol caafimaad qabta oo dheer.
Nicotinamide Adenine Dinucleotide (NAD) wuxuu ku jiraa qaabkiisa oksaydhka leh (NAD+) ama qaab la dhimay (NADH), kuwaas oo ah isku-xidhayaal muhiim ah oo ka mid ah tiro ka mid ah oxireductases.
SyncoZyems oo ah shirkaddii ugu horreysay ee hesha shirkadda wax soo saarka ceeriin ee FDA NDI NMN ee la ansixiyay, waxay si rasmi ah u aqbashay NMN maadaama nooc cusub oo agab ah laga yaabo in la aqbalo oo loo ansixiyo maaddooyinka kaabista cuntada ee Mareykanka. Waxaan sidoo kale ku takhasusnay hagaajinta maaraynta waxyaabaha iyo habka QC si aan u sii haysanno faa'iidada weyn ee ganacsiga yar yar ee Shiinaha ee jumlada ah ee Tayada ugu Fiican Qiimaha ugu Yar ee Kaabista Cuntada Beta Nicotinamide Mononucleotide Nmn CAS 1094-61-7, Waxaan rajeyneynaa inaan hubinno is-dhexgal ganacsi oo aad u yar oo lala yeesho macaamiisha adduunka oo dhan.
Jumlad Shiinaha ahShiinaha Nicotinamide Mononucleotide iyo NrHadda, si xirfad leh ayaan macaamiisha ugu siinaa alaabtayada ugu muhiimsan. Ganacsigeennu ma aha oo kaliya "iibso" iyo "iibso", laakiin sidoo kale waxaan diiradda saarnaa wax badan. Waxaan higsaneynaa inaan noqono alaab-qeybiyahaaga daacadda ah iyo iskaashiga muddada dheer ee Shiinaha. Hadda, waxaan rajeyneynaa inaan saaxiibo kula noqono.
