Aldolase (DERA)

Sharaxaad Gaaban:

ES-DERAs: Waxay si wax ku ool ah u kicin kartaa ku darista stereoselective ee ketones deeq-bixiyeyaasha aldehydes-ka qaataha. Intaa waxaa dheer, falcelinta waxaa lagu samayn karaa xal biyood oo pH dhexdhexaad ah iyada oo aan la isticmaalin tallaabooyin ilaalin gaar ah. Waxay ka tirsan yihiin fasalka I aldolase, kaas oo sameeya saldhigga Shiff ee habka katalytic-ga. Substrate-ku wuxuu si isku xiran ugu xiran yahay kooxda amino ee goobta firfircoon si uu u bilaabo jabka iyo sameynta xiriirka. Farqiga u dhexeeya DERAs iyo aldolases kale ayaa ah in substrate-yada ay katalysiiyaan ay yihiin aldehydes waxayna mari karaan isku-darka aldehydes ee joogtada ah.

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Faahfaahinta Badeecada

Calaamadaha Alaabta

Ku saabsan Aldolase:

Waxaa jira 8 nooc oo ah alaabada aldolase (Lambarka ES-DERA-101～ES-DERA-108) oo ay samaysay SyncoZymes. SZ-DERA waa qalab waxtar leh oo lagu kicinayo sameynta isku xidhka kaarboon-kaarboon ee enantioselective, taasoo soo saarta ilaa laba xarun oo chiral ah xaaladaha falcelinta fudud.

Nooca falgalka kicinta:

Habka kicinta:

Macluumaadka Badeecada:

Ensaymyada	Koodhka Badeecada	Faahfaahinta
Budada Ensaymka	ES-DERA-101~ ES-DERA-108	set ah 8 Aldolase, 50 mg midkiiba 8 shay * 50mg / shay, ama tiro kale
Qalabka Baaritaanka (SynKit)	ES-DERA-800	set ah 8 Aldolase, 1 mg midkiiba 8 shay * 1mg / shay

Faa'iidooyinka:

★ Baaxadda ballaaran ee substrate-ka.
★ Beddel sare.
★ Wax soo saar yar.
★ Xaalado falcelin fudud.
★ Deegaanka u wanaagsan.

Tilmaamaha isticmaalka:

➢ Caadiyan, nidaamka falgalka waa inuu ku jiraa substrate, xalka kaydka (pH falcelinta ugu fiican) iyo ES-DERA.
➢ Dhammaan noocyada ES-DERA ee u dhigma xaaladaha kala duwan ee falcelinta ugu wanaagsan waa in si gaar ah loo barto.
➢ ES-DERA waa in lagu daraa nidaamka falcelinta ugu dambeeya si loo ilaaliyo dhaqdhaqaaqa.
➢ Substrate-ka ama badeecadda leh feejignaan sare ayaa laga yaabaa inay joojiso dhaqdhaqaaqa ES-DERA. Si kastaba ha ahaatee, joojinta waxaa lagu yareyn karaa iyadoo lagu daro substrate-ka dufcaddii.