Cyclohexanone monooxygenase (CHMO)
Sharaxaad Gaaban:
Ku saabsan Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): Baeyer Villiger monooxygenase (BVMO) oo leh cyclohexanone oo ah substrate-ka, ayaa oksaydhi kara cyclohexanone una geyn kara cyclohexanol iyadoo la adeegsanayo oksijiin.
Waa nooc ka mid ah enzyme-ka ku tiirsan flavin. Flavin-ka oksaydhka leh waxaa loo yareeyaa flavin iyada oo loo marayo wareegga dhimista coenzyme II (NADPH) si loogu sameeyo oksaydheynta xigta. Sidaa darteed, cofactor NADPH ayaa lagama maarmaan u ah wareegga flavin. Waxaa jira 1 nooc oo keliya oo ah badeecada ensaymka CHMO (Lambarka sida ES-CHMO101) oo ay samaysay SyncoZymes, kaas oo loo isticmaali karo in lagu oksaydho cyclohexanone una beddelo cyclohexanone.
Nooca falgalka kicinta:
Moobayl/Wechat/WhatsApp: +86-13681683526
Iimayl:lchen@syncozymes.com
| Ensaymyada | Koodhka Badeecada | Faahfaahinta |
| Qalabka Baaritaanka (SynKit) | ES-CHMO-101 | 1 Ketoreductases, 1 mg midkiiba 1 shay * 1mg / shay |
★ Gaar ahaansho sare oo substrate ah.
★ Xulasho xooggan oo ku saabsan chiral.
★ Beddel sare.
★ Wax soo saar yar.
★ Xaalado falcelin fudud.
★ Deegaanka u wanaagsan.
➢ Caadiyan, nidaamka falcelinta waa inuu ku jiraa substrate, xalka kaydka, ensaymka, coenzyme iyo nidaamka dib u soo noolaynta coenzyme (tusaale ahaan gulukooska iyo glucose dehydrogenase).
➢ CHMO waa in lagu daraa habka falcelinta ugu dambeeya, ka dib marka pH iyo heerkulka la hagaajiyo xaaladda falcelinta.
Tusaale 1(Isku-darka cyclohexanol laga bilaabo cyclohexanol)(1):
Ku hay heerkul ka hooseeya -20 ℃ 2 sano.
Weligaa ha taaban xaalado daran sida: heerkul sare, pH sare/hoose iyo dareere dabiici ah oo xoog badan.
1. Friso, Marco, Appl Microbiol Biotechnol, 2017, 101 (20): 7557-7565
