Ketoreductase (KRED)
KRED oo ka socota SyncoZymes: Waxaa jira 191 nooc oo ah alaabada enzyme KRED (Lambarka sida ES-KRED-101~ES-KRED-291) oo ay soo saartay SyncoZymes.SZ-KRED waxaa si weyn loogu isticmaali karaa regio- iyo hoos u dhigista istiraatijiyadeed ee aldehydes, beta-ketone esters, α-ketone esters iyo ketones.
Nooca falcelinta catalytic:
| Enzymes | Koodhka badeecada | Tilmaamid |
| Budada Enzyme | Budada Enzyme | 187 Ketoreductases, 50 mg 187 walxood * 50mg / shay, ama tiro kale |
| Qalabka Baaritaanka (SynKit) | ES-KRED-18100 | 181 Ketoreductases, 1 mg midkiiba 181 shay * 1mg / shay |
★ gaar ahaan substrate-ka sare.
★ Xulasho xoog leh oo chiral ah.
★ Waxtarka beddelka sare.
★ Alaabooyin ka yar
★ Xaalado falcelin fudud.
★ deegaan ahaan.
➢ Baadhitaanka enzyme waa in lagu sameeyaa substrates gaar ah sababtoo ah gaar ahaan substrate-ka, oo la helo ensaym ka kaca substrate-ka bartilmaameedka leh ee saamaynta ugu fiican.
➢ Weligaa ha la xiriirin xaaladaha ba'an sida: heerkulka sare, pH sare/hoose iyo dareere organic leh oo leh feejignaan sare.
➢ Caadiyan, habka falcelinta waa in ay ku jiraan substrate, xal kaydiyaha, coenzymes (NAD(H) ama NADP(H)), nidaamka dib u soo kabashada coenzyme (tusaale gulukoos iyo gulukoos dehydrogenase).
➢ KRED waa in lagu daraa ugu danbeyn habka falcelinta, ka dib marka pH iyo heerkulka lagu hagaajiyo xaalada falcelinta.
➢ Dhammaan noocyada KRED waxay leeyihiin xaalado falcelin wanaagsan oo kala duwan, marka mid kasta oo iyaga ka mid ah waa in si gaar ah loo darso.
Tusaale 1(1):
Tusaale 2(2):
1. Li Z, Liu WD, Chen X, iyo tall.Tetrahedron, 2013, 69, 3561-3564.
2. Ni Y, Li CX, Ma HM, iyo Tal.Appl Microbiol Biotechnol, 2011, 89: 1111-1118.
