Cyclooxygenase (COX)

Sharaxaad Gaaban:

Ku saabsan Cyclooxygenase

ES-COX (Cyclooxygenase): waxay kicisaa beddelka curaarta C=C oo loo beddelo epoxide.Waxaa jira 11 nooc oo ah alaabada enzyme COX (Lambarka sida ES-COX101 ~ ES-COX-111) oo ay soo saartay SyncoZymes.Marka loo eego hababka kicinta ee kala duwan, COX ee SyncoZymes waxaa loo qaybiyaa haloperoxidase iyo styrene monooxygenase.ES-COX101, 102, 107-111 waxay iska leeyihiin haloperoxidase, halka ES-COX103-106 ay iska leeyihiin styrene monooxygenase.

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Faahfaahinta Alaabta

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Ku saabsan Cyclooxygenase:

Nooca falcelinta catalytic:

Haloperoxidase:

Styren monooxygenase:

Macluumaadka Alaabta:

Enzymes	Koodhka badeecada	Tilmaamid
Budada Enzyme	ES-COX-101~ ES-COX-110	10 NADH Cyclooxygenase, 50 mg 10 shayba * 50mg/shay, ama tiro kale

Faa'iidooyinka:

★ gaar ahaan substrate-ka sare.
★ Xulasho xoog leh oo chiral ah.
★ beddelaad sare.
★ Alaabooyin ka yar
★ Xaalado falcelin fudud.
★ deegaan ahaan.

Tilmaamaha isticmaalka:

➢ Caadiyan, habka falcelinta haloperoxidase waxa ku jira: substrate, buffer, enzyme, H2O2 iyo halogen ion.Habka falcelinta Styrene monooxygenase waxaa ka mid ah substrate, buffer, enzyme, coenzyme iyo nidaamka dib u soo kabashada coenzyme.
➢ COX waa in lagu daraa ugu danbeyn habka falcelinta, ka dib marka pH iyo heerkulka lagu hagaajiyo xaalada falcelinta.

Tusaalooyinka Codsiga:

Tusaale 1 (Synthesis of epoxy styrene derivatives oo ka soo jeeda styrene)⁽¹⁾:

Fiiro gaar ah: Tusaalooyinka codsiga iyo tixraacyada waxaa loogu talagalay in lagu muujiyo baaxadda codsiga ee COX si ay u fududaato fahamka, oo aan u dhigmin ensaymka gaarka ah ee SyncoZymes.