β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. waa hormuudka soo saaraha iyo soo saaraha β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS: 53-59-8) oo leh tayo sare.Waxaan bixin karnaa COA, gaarsiinta adduunka oo dhan, tiro yar iyo tiro badan oo la heli karo.Haddii aad xiisaynayso alaabtan, fadlan u soo dir macluumaad faahfaahsan oo ay ku jiraan lambarka CAS, magaca badeecada, tirada noo soo dir.Fadlan la xidhiidh:lchen@syncozymes.com
| Magaca Kiimikada | β-Nicotinamide adenine dinucleotide fosfate hydrate |
| La mid ah | β-Nicotinamide adenine dinucleotide fosfate hydrate |
| Lambarka CAS | 53-59-8 |
| Miisaanka Molecular | 743.41 |
| Qaanuunka molecular | C21H28N7O17P3 |
| EINECS Maya. | 200-178-1 |
| heerkulka kaydinta. | Ku hay meel mugdi ah, jawi aan fiicneyn, ku kaydi qaboojiyaha, ka hooseeya -20 ° C |
| milmayn | H2O: 50 mg/ml, cad, waxoogaa huruud ah |
| pka | pKa1 3.9;pKa2 6.1 ( saacada 25 ℃) |
| ugu badnaan | 260nm ( shid) |
| Merck | 14,6348 |
| Nidaamka Diiwaanka Walxaha EPA | Adenosine 5'- (trihydrogen diphosphate), 2'- (dihydrogen phosphate), P'.fwdarw.5'-ester leh 3-(aminocarbonyl) -1-.beta.-D-ribofuranosylpyridinium, cusbada gudaha (53-59- 8) |
| Shayga Tijaabada | Tilmaamaha |
| Muuqashada | Caddaan ilaa budo huruud ah |
| Solubility | 200mg/ml oo biyo ah |
| Qiimaha pH (100mg/ml) | 5.0-7.0 |
| Falanqaynta UV Spectral 260 nm iyo pH 7.5 | (18±1.0)×10³L/mol/cm |
| Nuxurka (iyada oo loo eegayo falanqaynta enzymatic oo leh G6PDH at pH 7.5, iyadoo la isticmaalayo spectrophotometer, abs.340nm, ku salaysan anhydrous) | ≥90.0% |
| Daahirnimada (waxaa leh HPLC,% area) | ≥95.0% |
| Waxyaabaha biyaha ka kooban (waxaa qoray KF) | ≤5% |
Xidhmada:Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Si adag ugu xidh mugdiga, si aad u kaydiso wakhti dheer ku hayso 2 ~ 8 ℃.
NADP waa koenzyme, kaas oo ah walax ay ku jiraan nicotinamide adenine dinucleotide iyo molecule fosfateed ay ku xidhan yihiin dammaanad ester ah, oo si ballaaran u jirta.dunida noolaha.Alaabta kiimikada ah, nuugista spectrum, qaabka redox, iwm. waxay la mid yihiin NAD (Coenzyme I).NADP waxaa si weyn loogu isticmaali karaa falcelintaKatalalised by khamriga kala duwan dehydrogenases, ketoreductases iyo oxidoreductases kale.Sida: waxaa lagu dhimi karaa NADPH by dehydrogenases badan sidasida 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44).Si kastaba ha ahaatee, daruuri maaha inay la falgaliso qaar badandehydrogenases ee isticmaala NAD, sidoo kale si toos ah uguma oksijiyeen silsiladda neefsashada.Si ka duwan NAD, waxay inta badan ku jirtaa xaalad hoos u dhacday unugyada noolaha hawada.
Marka loo eego isticmaalka alaabta, waxaa loo qaybin karaa darajooyinka soo socda: darajada biotransformation, darajada reagent ogaanshaha, heerka cuntada caafimaadka.
Darajada Biotransformation: Waxaa loo isticmaali karaa isku-darka dhexdhexaadiyeyaasha dawooyinka iyo API-yada, badiyaa leh enzymes-ka-taliya, sida ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), gulukoos dehydrogenase (GDH), iwm. Sug.
Darajada reagent ogaanshaha: Iyada oo leh noocyo kala duwan oo enzymes ogaanshaha, sida alaabta ceeriin ee xirmooyinka ogaanshaha.
Heerka cuntada caafimaadka: Codsiga kabka cuntada ee NADP wuxuu inta badan ku jiraa habka cilmi-baarista iyo horumarinta.
