β-Nicotinamide Mononucleotide (NMN)
Dhawaan, waxaa jira war wanaagsan oo ku saabsan berrinka NMN - ka dib markii ay si adag u eegis ku sameeyeen guddiga xirfadlayaasha ah ee Maamulka Cuntada iyo Dawooyinka ee Maraykanka (FDA) ururka awoodda leh, NMN alaabta ceeriin ee Shangke Biopharmaceutical (Shanghai) Co., Ltd. sida "Shangke Bio") ay ansixisay Maraykanka FDA NDI ansixinta waxay xaqiijinaysaa in alaabta ceeriin ee NMN si rasmi ah loogu isticmaali karo wax soo saarka, iibinta iyo kor u qaadida kaabista cuntada ee Maraykanka, waxaana laga heli karaa sarkaalka FDA. Mareegta sida alaab cusub oo dheeri ah oo cayriin ah, lambarka 1247.
FDA NDI waa nidaamka shahaadaynta ugu muhiimsan ee suuqa Maraykanka.Helitaanka shahaadadan macnaheedu maaha oo kaliya in badbaadada iyo tayada alaabta Shangke Bio ay yihiinsi heer sare ah loo aqoonsan yahay, laakiin sidoo kale waxay ku habboon tahay horumarka joogtada ah ee halbeegga ee warshadaha NMN mustaqbalka fog.
| Magaca Kiimikada | β-Nicotinamide Mononucleotide |
| La mid ah | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
| Lambarka CAS | 1094-61-7 |
| Miisaanka Molecular | 334.22 |
| Qaanuunka molecular | C11H15N2O8P |
| EINECS wuxuu leeyahay: | 214-136-5 |
| barta dhalaalaysa | 166 °C (dac.) |
| heerkulka kaydinta. | -20°C |
| milmayn | DMSO (wax yar, kuleyl), Methanol (wax yar), Biyo (wax yar) |
| qaab | Adag |
| midab | Cadaan ilaa Jaalle |
| Merck | 13,6697 |
| BRN | 3570187 |
| Xasilooni | Aad u Hygroscopic |
| InChiKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Shayga Tijaabada | Tilmaamaha |
| Muuqashada | Caddaan iyo budo crystalline ah |
| Maadada sodium | ≤1% |
| Qiimaha pH (100mg/ml) | 2.0 ~ 4.0 |
| daahirnimo | ≥99.0% |
| Biyaha ku jira | ≤1% |
| Biraha culus | <10ppm |
| Arsenic | <0.5pm |
| Hogaamin | <0.5pm |
| Meerkuri | <0.1pm |
| Cadmium | <0.5pm |
| Haraaga millatariga | Ethanol≤1000ppm |
| Wadarta tirada Microbial Aerobic | <750cfu/g |
| Khamiirka & Caaryada | <25cfu/g |
| Wadarta coliform | ≤0.92MPN/g |
| E. Coli | xun |
| Salmonella | xun |
| Staph.Aureus | xun |
| Qiimaynta (oo ku salaysan anhydrous) | ≥99.0% |
| Sicir bararka | ≥95% |
| Cufnaanta weyn | Warbixin wixii macluumaad ah |
Xidhmada:Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha cidhiidhiga ah, iftiinka u adkaysta, kaydinta muddada dheer ku hay 2 ~ 8 ° C ama ka hooseeya.
Nicotinamide Mononucleotide (NMN) waa nooc cusub oo fitamiin B3 ah kaas oo ah 1 tillaabo horudhac u ah NAD+ (Nicotinamide Adenine Dinucleotide).NMN waa soo-celinta unugyada NAD + ee ugu horreeya ee lagu xaqiijiyo waxtarka si loo soo celiyo unugyada vivo.
Nicotinamide Adenine Dinucleotide (NAD) waa mid ka mid ah unugyada ugu muhiimsan uguna xiisaha badan ee jirka.Waxaa looga baahan yahay in ka badan 500 falcelin enzymatic ah waxayna ka ciyaartaa door muhiim ah nidaaminta ku dhawaad dhammaan hababka noole ee waaweyn (Ansari iyo Raghava, 2010).Waxa dhan ka sii sarreeya, waxa laga yaabaa inay noo ogolaato inaan ku noolaano nolol caafimaad leh oo dheer.
Nicotinamide Adenine Dinucleotide (NAD) waxay ku jirtaa qaabkeeda oksaydhsaydhka ah (NAD+) ama qaab la dhimay (NADH), kuwaas oo ah isku-xidhayaasha muhiimka ah ee tiro oxireductases ah.
SyncoZyems oo ah tii ugu horreysay ee hesha FDA NDI NMN oo ay ogolaatay shirkad wax-soo-saar alaab cayriin ah, waxay matashaa sarkaalka FDA aqbal NMN maadaama nooc cusub oo walxo bilaabi karo in la aqbalo oo loo oggolaado maaddooyinka kabka cuntada ee Maraykanka.
