β-Nicotinamide Mononucleotide (NMN)
Dhawaan, waxaa jira war wanaagsan oo ku saabsan NMN - ka dib markii ay si adag u eegeen guddiga xirfadeed ee hay'adda awoodda u leh Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA), agabka cayriin ee NMN ee Shangke Biopharmaceutical (Shanghai) Co., Ltd. (oo hadda loogu yeero "Shangke Bio") ay ansixisay oggolaanshaha FDA NDI ee Mareykanka ayaa xaqiijinaysa in agabka cayriin ee NMN si rasmi ah loogu isticmaali karo wax soo saarka, iibinta iyo kor u qaadista kaabayaasha cuntada ee Mareykanka, waxaana laga heli karaa bogga rasmiga ah ee FDA oo ah agab cayriin oo cusub oo dheeri ah oo cunto ah, lambar 1247.
FDA NDI waa nidaamka shahaadada ugu muhiimsan suuqa Mareykanka. Helitaanka shahaadadan macnaheedu maahan oo keliya in badbaadada iyo tayada alaabada Shangke Bio ay yihiin kuwo la awoodi karo.si heer sare ah loo aqoonsan yahay, laakiin sidoo kale waxay gacan ka geysaneysaa horumarinta joogtada ah ee heerarka warshadaha NMN mustaqbalka fog.
| Magaca Kiimikada | β-Nicotinamide Mononucleotide |
| Erayo isku mid ah | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-FOSBAHEED |
| Lambarka CAS | 1094-61-7 |
| Miisaanka Molekulerka | 334.22 |
| Qaacidda Molekuleerigga | C11H15N2O8P |
| EINECS wuxuu leeyahay: | 214-136-5 |
| Barta dhalaalaysa | 166 °C(Diseembar) |
| heerkulka kaydinta. | -20°C |
| milmida | DMSO (Waxoogaa yar, Kulayl leh), Methanol (Waxoogaa yar), Biyo (Waxoogaa yar) |
| qaab | Adag |
| midab | Cadaan ilaa Jaalle |
| Merck | 13,6697 |
| BRN | 3570187 |
| Xasilloonida: | Aad u Hygroscopic ah |
| InChiKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Shayga Tijaabada | Tilmaamaha |
| Muuqaalka | Budada kristalinta cad ilaa caddaan ah |
| Waxyaabaha soodhiyamku ka kooban yahay | ≤1% |
| Qiimaha pH (100mg/ml) | 2.0~4.0 |
| Daahirnimo | ≥99.0% |
| Biyaha ku jira | ≤1% |
| Biraha culus | <10ppm |
| Arsenik | <0.5ppm |
| Hoggaanka | <0.5ppm |
| Meerkuriga | <0.1ppm |
| Cadmium | <0.5ppm |
| Hadhaaga dareeraha ah | Etanool ≤1000ppm |
| Wadarta Tirada Microbial-ka Hawada Sare | <750cfu/g |
| Khamiirka iyo Caaryada | <25cfu/g |
| Wadarta coliform | ≤0.92MPN/g |
| E. Coli | Taban |
| Salmonella | Taban |
| Staph. Aureus | Taban |
| Baaritaan (oo ku salaysan biyo la'aan) | ≥99.0% |
| Heerka kala-goynta | ≥95% |
| Cufnaanta badan | Ka warbixi macluumaadka |
Xirmada:Dhalo, bacda aluminium-ka, 25kg/Durbaan Kaarboor, ama sida waafaqsan shuruudaha macaamiisha.
Xaaladda Kaydinta:Ku hay weelal adag oo iftiin u adkaysta, si aad u kaydiso muddo dheer, ku hay heerkul ah 2-8°C ama ka hooseeya.
Nicotinamide Mononucleotide (NMN) waa nooc cusub oo fiitamiin B3 ah kaas oo ah horudhac 1 tallaabo ah oo loo maro NAD+ (Nicotinamide Adenine Dinucleotide). NMN waa soo-celinta unugyada NAD+ ee ugu horreysa ee la xaqiijiyay inay waxtar u leedahay soo celinta unugyada gudaha jirka.
Nicotinamide Adenine Dinucleotide (NAD) waa mid ka mid ah molecules-ka ugu muhiimsan uguna xiisaha badan jirka. Waxaa looga baahan yahay in ka badan 500 oo falgal enzymatic ah waxayna door muhiim ah ka ciyaartaa nidaaminta ku dhawaad dhammaan hababka bayoolojiga ee waaweyn (Ansari iyo Raghava, 2010). Waxa ugu muhiimsan, waxay noo ogolaan kartaa inaan ku noolaano nolol caafimaad qabta oo dheer.
Nicotinamide Adenine Dinucleotide (NAD) wuxuu ku jiraa qaabkiisa oksaydhka leh (NAD+) ama qaab la dhimay (NADH), kuwaas oo ah isku-xidhayaal muhiim ah oo ka mid ah tiro ka mid ah oxireductases.
Shirkadda SyncoZyems oo ah shirkaddii ugu horreysay ee hesha shirkadda wax soo saarka ceeriin ee FDA NDI NMN ee la ansixiyay, ayaa si rasmi ah u aqbashay NMN maadaama nooc cusub oo agab ah laga yaabo in la aqbalo oo loo ansixiyo maaddooyinka dheeraadka ah ee cuntada ee Mareykanka.
