Nitrilase (NIT)
Sharaxaad Gaaban:
Ku saabsan Nitrilase
ES-NITs: Si toos ah ugu beddelo kooxda cyanide kooxda karboxyl, si ay u diyaariyaan karboxilic acid, taas oo si weyn loogu isticmaalo daawada, ilaalinta deegaanka, warshadaha kiimikada, cuntada lagu daro, dhar, wax soo saarka beeraha iyo beeraha kale.
Waxaa jira 40 nooc oo badeecooyin Nitrilase ah (NIT) ah (Lambarka ES-NIT-101~ES-NIT-140) oo ay soo saartay SyncoZymes.ES-NIT waa qalab faa'iido leh oo lagu kicinayo isku-darka asiidhyada karboksilic ee chiral iyada oo loo marayo regio- iyo stereoselective hydrolysis ee noocyo kala duwan oo aliphatic iyo nitriles udgoon.
Nooca falcelinta catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
iimayl:lchen@syncozymes.com
| Enzymes | Koodhka badeecada | Tilmaamid |
| Budada Enzyme | ES-NIT-101~ ES-NIT-140 | 40 Nitrilase ah, 50 mg midkiiba 40 shay * 50mg/shay, ama tiro kale |
| Qalabka Baaritaanka (SynKit) | ES-NIT-4000 | 40 Nitrilase ah, 1 mg midkiiba 40 shay * 1mg / shayga |
★ gaar ahaan substrate-ka sare.
★ beddelaad sare.
★ Alaabooyin ka yar
★ Xaalado falcelin fudud.
★ deegaan ahaan.
➢ Caadiyan, habka falcelinta waa in lagu daraa substrate, xallinta wax-ka-qabashada (pH) iyo ES-NIT.
➢ Dhammaan ES-NIT-yada waxa lagu tijaabin karaa siday u kala horreeyaan habka falcelinta ee sare ama Qalabka Baadhista NIT (SynKit NIT).
➢ Dhammaan noocyada ES-NITs ee u dhigma xaaladaha kala duwan ee falcelinta ugu wanaagsan waa in si gaar ah loo darso.
➢ Substrate-ka sare u kaca ama badeecada leh ayaa laga yaabaa inay hor istaagto dhaqdhaqaaqa ES-NIT.Si kastaba ha ahaatee, xannibaadda waxaa lagu nafisi karaa marka lagu daro qayb ka mid ah substrate.
Tusaale 1 (Synthesis of nicotinic acid)(1):
Tusaale 2 (Synthesis of (R)-(-)-mandelic acid)(2):
Tusaale 3 (Synthesis of baclofen)(3):
Tusaale 4 (Synthesis of glycolic acid)(4):
Ka dhig 2 sano ka hooseeya -20 ℃.
Weligaa ha la xiriirin xaaladaha ba'an sida: heerkulka sare, pH sare/hoose iyo dareeraha organic-fiirsashada sare leh.
1 Mathew CD, Nagasawa T, Kobayashi M, iyo tal.Appl.Deegaanka.Microbiol, 1988, 54 (4): 1030.
2 Yamamoto K, Oishi K, Fujimatsu I, iyo Tal.Appl.Deegaanka.Microbiol, 1991, 57 (10): 3028.
3 Xu MZ, Ren J, Gong JS, iyo tall.GarkaJ. Biotechnol, 2013, 29 (1): 31.
4 Wu S, Fogiel AJ, Petrillo KL, iyo tale.BiotechnolBioeng., 2008, 99 (3): 717.
