Transaldolase (TAL)
Sharaxaad Gaaban:
Ku saabsan Transaldolase
ES-TAL (Transaldolase): badiyaa waxaa loola jeedaa threonine transaldolases, taas oo kicin karta falcelinta si ay u abuurto derivatives β-hydroxyphenylalanine leh threonine iyo benzaldehyde derivatives.TAL waa enzyme ku tiirsan PLP.Waxa jira kaliya 1 nooc oo ah badeecada TAL enzyme (Lambarka sida ES-TAL101) ee ay samaysay SyncoZymes, kaas oo loo isticmaali karo in lagu sameeyo β-hydroxyphenylalanine iyo ka-soo-saarkeeda.
Nooca falcelinta catalytic:
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iimayl:lchen@syncozymes.com
★ gaar ahaan substrate-ka sare.
★ Xulasho xoog leh oo chiral ah.
★ beddelaad sare.
★ Alaabooyin ka yar
★ Xaalado falcelin fudud.
★ deegaan ahaan.
➢ Caadiyan, habka falcelinta waa in ay ku jiraan substrate, xal buffer, enzyme, PLP, Mg2+.
TAL waa in lagu daraa ugu danbeyn habka falcelinta, ka dib marka pH iyo heerkulka lagu hagaajiyo xaalada falcelinta.
Tusaale 1 (Synthesis of (2S, 3R) -p-methylsulfonyl phenylserine ka p-methylsulfonyl benzaldehyde iyo threonine)(1):
Ka dhig 2 sano ka hooseeya -20 ℃.
Weligaa ha la xiriirin xaaladaha ba'an sida: heerkulka sare, pH sare/hoose iyo dareeraha organic-fiirsashada sare leh.
1. CN109836362B
