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Oxynitrilases (HNL)
Ku saabsan oxynitrilases
ES-HNLs: Enzyme fasalka kaas oo si firfircoon u kicinaya ku darida HCN ee aldehydes (ketones) si loo helo khamriga cyanide nooca R ama S, kaas oo si fudud loogu beddeli karo noocyo badan oo daroogo ah ama dhexdhexaadin daroogo iyada oo loo marayo habka kiimikada.
Waxaa jira 29 nooc oo ah alaabada oxynitrilase (Lambarka ES-HNL-101～ES-HNL-129) oo ay soo saartay SyncoZymes.SZ-HNL waa qalab waxtar u leh regio- iyo stereo-xushay synthesis of (R) -cyanohydrins ama (S) -cyanohydrins ka noocyo kala duwan oo uduga, aliphatic iyo heterocyclic aldehyde ama xataa ketones.
Nooca falcelinta catalytic:
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Nitro reductase (NTR)
Ku saabsan nitro reductase
ES-NTRs: Waa flavoenzymes kuwaas oo kicinaya hoos u dhigista NAD (P) H-ku-tiirsanaanta ee kooxaha nitroomatic iyo nitroheterocyclic xeryahooda hydroxylamino iyo/ama soosaarayaasha amino.Waxaa si weyn loo isticmaalaa in synthesis organic of aromatic hydroxylamine iyo amine udgoon, therapy burooyinka, ogaanshaha bayooloji iyo xaalufinta wasakh deegaanka.Waxaa jira 12 nooc oo ah alaabada Nitro reductase (NTR) (Lambarka sida ES-NTR-101~ES-NTR-112) ee ay soo saartay SyncoZymes.
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Aldolase (DERA)
ES-DERAs: Waxay si wax ku ool ah u kicin kartaa isugeynta istiraatijiga ah ee ketones deeq-bixiyeyaasha ee aldehyde soo-qabtayaasha.Waxaa intaa dheer, falcelinta waxaa lagu samayn karaa xal aqueous ah pH dhexdhexaad ah iyada oo aan tallaabooyin ilaalin gaar ah.Waxay ka tirsan yihiin fasalka I aldolase, kaas oo ka dhigaya saldhigga Shiff ee habka kicinta.Substrate-ka ayaa si wadajir ah ugu xidhan kooxda amino ee goobta firfircoon si loo bilaabo jebinta iyo samaynta curaarta.Farqiga u dhexeeya DERAs iyo aldolases kale waa in substrate-yada ay kiciyaan ay yihiin aldehyde oo ay mari karaan uumi aldehydes joogto ah.
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Cytochrome P450 monooxygenase (CYP)
Ku saabsan CYP
ES-CYPs: Waa nooc ka mid ah enzymes redox oo leh mercaptan-heme oo ah xarun firfircoon si ay u kiciso wareejinta oksijiinta.Waxay yihiin oxygenases-ka-baxa waxayna u baahan yihiin heme si ay u dhaqaajiyaan ogsijiinta.
Cytochrome P450 monooxygenase katalyze oxidation, Epoxidation iyo hydroxylation of alkyl, hydroxylation iyo oxidation of ammonia, oxidation of baaruud, dealkylation (oxygen, baaruud, ammonia), fuuqbaxa oxidative, deamination iyo dehalogenation.
Waxaa jira 8 nooc oo cytochrome P450 monooxygenase ah (Lambarka ES-CYP-101-ES-CYP-108) oo ay soo saartay SyncoZymes.Mobile/Wechat/WhatsApp: +86-13681683526
iimayl:lchen@syncozymes.com
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Alcohol oxidase (AOX)
Ku saabsan oxidase khamriga
ES-AOXs: Ensaymes-yadani waxay awoodaan inay kiciyaan oksaydhka alkolada dufanka leh ama aryl-alcohols si ay u sameeyaan aldehyde.Waxay isticmaalaan ogsijiin molecular laakiin uma baahna cofactor dibadda ah oo lagu daro, iyo hydrogen peroxide ayaa la soo saaray.
Waxaa jira 6 nooc oo ah alaabada alkohol-oxidases (Lambarka sida ES-AOX-101~ES-AOX-106) oo ay soo saartay SyncoZymes.ES-AOX101 iyo ES-AOX102 waxay door bidaan substrate-ka alkolada aliphatic, ES-AOX103~ ES-AOX105 waxay door bidaan alkolada caraf udgoon, iyo ES-AOX106 waa kolestarool oxidase.SZ-AOX waa qalab faa'iido leh si loo kiciyo oksaydhka alkolada dufanka leh ama alkolada aryl si loo soo saaro aldehyde.
Nooca falcelinta catalytic:
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D-Amino acid dehydrogenase (D-AADH)
Ku saabsan D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): ensaymes oo yarayn kara 2-keto acid una dhigma D-amino acid.Dareen-celinta waxay u baahan tahay NADP (H) iyo ku-deeqaha ammonia-ga aan noolayn (sida ammonia ama ammonium ion).Waxaa jira 17 nooc oo ah D-amino acid dehydrogenases (Lambarka ES-DAADH-101~ ES-DAADH-117) oo ay soo saartay SyncoZymes.
Nooca falcelinta catalytic:
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Esterase&Lipase (PLE&CALB)
Ku saabsan Esterase&Lipase
ES-PLEs: Waa nooc ka mid ah hydrolases oo kicinaya samaynta iyo jebinta curaarta esterka.Waxay ka qaybqaadan karaan noocyo badan oo falcelinta biochemical ah, sida esterification, transesterification iyo hydrolysis.Waxaa si weyn looga isticmaalaa dhinacyo badan sida habaynta cuntada, warshadaha kiimikada, biomedicine, dawada chiral iyo daaweynta deegaanka.
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Epoxide hydrolase (EH)
Ku saabsan epoxide hydrolase
EH waa ether hydrolase kaas oo kicinaya hydrolysis stereoselective ee epoxides jinsiyadeed si ay u soo saaraan 1, 2-diol iyo epoxides muuqaal ahaan firfircoon, kuwaas oo loo isticmaali karo xallinta chiral ee epoxides ama diyaarinta diols chiral.Waxaa si weyn loogu isticmaalaa daawada iyo qaybaha kale.Waxaa jira 3 nooc oo ah alaabada epoxide hydrolases (Lambarka sida ES-EH-101～ES-EH-103) oo ay soo saartay SyncoZymes.ES-EH waa qalab faa'iido leh oo lagu kicinayo isku-darka alkolada chiral iyada oo loo marayo hydrolysis stereoselective ee aliphatic iyo aromatic epoxides.
Nooca falcelinta catalytic:
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iimayl:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Ku saabsan Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH waxay kicisaa fuuq-baxa ammonium formate si loo soo saaro kaarboon dioxide iyo ammonia, oo loo yareeyo NAD ilaa NADH oo leh NAD sida soo-dhoweeyaha elektaroonigga ah.FDH waxaa badanaa loo isticmaalaa dib u soo kabashada coenzyme NADH.Waxaa jira 4 nooc oo ah alaabada enzyme FDH (ES-FDH-101~ES-FDH-104) oo ay samaysay SyncoZymes, kuwaas oo ES-FDH102 ay leedahay waxqabadka ugu sarreeya waana tan inta badan lagu taliyay FDH.
Nooca falcelinta catalytic:
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iimayl:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Ku saabsan Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH waxay kicisaa fuuq-baxa gulukooska si ay u soo saarto gluconic acid (lactone), oo ay hoos u dhigto NAD (P) + ilaa NAD (P) H, oo leh NAD (P)+ sida soo-dhoweeyaha elektaroonigga ah.GDH waxaa badanaa loo isticmaalaa dib-u-soo-nooleynta coenzyme NAD (P) H ee beeraha biocatalysis oo leh enzyme kale oo muhiim ah.Waxaa jira 10 nooc oo alaabada enzyme GDH ah (ES-GDH-101~ES-GDH-110) oo ay samaysay SyncoZymes, kuwaas oo ES-GDH110 ay leedahay waxqabadka ugu sarreeya waana tan inta badan lagu taliyay GDH.
Nooca falcelinta catalytic:
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iimayl:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Ku saabsan Monoamine oxidase
ES-MAO (Monoamine oxidase): MAO waxay kicisaa deamination oxidative ee monoamines si ay u soo saarto hydrogen peroxide, ammonia iyo aldehyde u dhigma.Habka catalytic, oksijiinta ayaa lagama maarmaan u ah oksidat ahaan.Waxaa jira 6 nooc oo ah alaabada enzyme MAO (Lambarka ES-MAO-101～ES-MAO-106) oo ay samaysay SyncoZymes, kaas oo loo isticmaali karo deamination oxidative ee xeryahooda monoamine.
Nooca falcelinta catalytic:
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iimayl:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Ku saabsan Lactate dehydrogenase
Waxaa jira 1 nooc oo ah badeecada enzyme LDH (Lambarka ES-LDH) ee ay soo saartay SyncoZymes.LDH waxay kicin kartaa dhimista pyruvate ilaa L-lactic acid, ama yaraynta asiidhyada α-keto kale ee la midka ah.Inta lagu jiro nidaamka catalysis, NADH waxay lagama maarmaan u tahay gaadiidleyda hydrogen.
Nooca falcelinta lactate dehydrogenasekalytic
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