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Imine reductase (IRED)
Ku saabsan Imine reductase
ES-IRED: Waa nooc ka mid ah ensaymes kuwaas oo kicinaya dhimista curaarta C=N ee curaarta CN.Waxay iska leedahay enzyme redox, oo leh coenzyme NADPH ee gaadiidka hydrogen.Marka loo eego doorbidida chiral ee alaabooyinka, waxaa loo qaybin karaa R-IRED iyo S-IRED.Syncozymes waxay soo saartay 15 imine reductases (lambareeyay ES-IRED-101-ES-IRED-115), kuwaas oo si ballaaran loogu isticmaali karo hoos u dhigista dib-u-doorashada iyo hoos u dhigista stereosective ee imines si loogu diyaariyo amines chiral.
Nooca falcelinta catalytic:
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Nitrile reductase (NRED)
Ku saabsan Nitrile reductase
Waxaa jira 3 nooc oo ah badeecada enzyme NRED (Lambarka sida ES-NRED101 ~ ES-NRED103) oo ay soo saartay SyncoZymes.NRED waxay kicin kartaa dhimista kooxda nitrile si loo amiinto.Inta lagu jiro nidaamka catalysis, NADPH ayaa loo baahan yahay sida gaadiid-qaade hydrogen ah.
Nooca falcelinta nitrile reductasecatalytic
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Phenylalanine dehydrogenase (PDH)
Ku saabsan Phenylalanine dehydrogenase
ES-PDH: Waa nooc ka mid ah oxidoreductase.Dareen-celinta togan waxay kicin kartaa deamination oksaydhiyaha ee cusbada L phenylalanine joogitaanka NAD si ay u soo saarto cusbada phenylpyruvate, falcelinta gadaashana waxay kicin kartaa isku dhafka milixda amino acid ee u dhigma ee cusbada phenylpyruvate.Syncozymes waxay soo saartay 8 shay oo ah phenylalanine dehydrogenase (lambareeyay ES-PDH-101~ES-PDH-108).ES-PDH waxaa loo isticmaali karaa in lagu diyaariyo cusbada phenylalanine ama milixda amino acid ee u dhigma ee laga helo cusbada fenylpyruvic
Nooca falcelinta catalytic:
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Leucine Dehydrogenase (LeuDH)
Ku saabsan Leucine dehydrogenase
Waxaa jira 1 nooc oo ah badeecada enzyme LeuDH (Lambarka ES-LeuDH-101) ee ay soo saartay SyncoZymes.LeuDH waxay kicin kartaa ammoniation-ka yar ee 4-methylbutanoic acid (milix) ilaa L-leucine ama oksaydhka leucine ilaa 4-methylbutanoic acid.ES-LeuDH waxay sidoo kale kicin kartaa hamiga yaraynta asiidhyada α-keto ee leh qaab dhismeed la mid ah si loo diyaariyo soosaarayaasha amino acid ee u dhigma.Inta lagu jiro nidaamka catalysis, NADH waxay lagama maarmaan u tahay gaadiidleyda hydrogen.
Nooca falcelin dehydrogenasekalytic Leucine
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Threonine deaminase (TDA)
Ku saabsan Threonine deaminase
ES-TDA (Threonine deaminase): waa borotiinka fosfateedka pyridoxal kaas oo kicinaya deamination ee threonine si uu u soo saaro 2-ketobutyric acid iyo ammonia.Pyridoxal 5-phosphate waa lagama maarmaan sida coenzyme ee nidaamka catalytic.Waxaa jira kaliya 1 nooc oo ah badeecada enzyme TDA (Lambarka ES-TDA) ee ay samaysay SyncoZymes, kaas oo loo isticmaali karo in lagu diyaariyo 2-ketobutyric acid ama waxyaabaha ka soo baxa ee threonine.
Nooca falcelinta catalytic:
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Amine Dehydrogenase (AmDH)
Ku saabsan Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): ensaymes oo kicin kara ammoation kooxda karbonyl oo u yarayn karta kooxda amino.Waa koenzyme NADH ku tiirsanaanta enzyme, NADH waxay u shaqeysaa sidii gudbiye haydrojiin ah.Waxaa jira 4 nooc oo ah alaabada enzyme AmDH (Lambarka sida ES-AmDH101～ES-AmDH104) oo ay samaysay SyncoZymes, kaas oo loo isticmaali karo dib-u-soo-doorasho-soo-saarka aldehyde iyo ketones.
Nooca falcelinta catalytic:
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Nucloside phosphoryalse (NP)
Ku saabsan fosforyaalse nucleoside
Waxaa jira 3 nooc oo ah alaabada enzyme NP (Lambarka sida ES-NP-101~ ES-NP-103) oo ay soo saartay SyncoZymes.ES-NP-101 waa purine nucleoside phosphorylase, ES-NP-102 iyo ES-NP-103 waa pyrimidine nucleoside phosphorylase.Nucleosidephosphorylase waxay u kala jajabisaa nucleosides oo u kala baxa saldhigyada iyo fosfatka pentose.Nucleoside phosphorylase waxaa loo qaybin karaa purine nucleoside phosphorylase iyo pyrimidine nucleoside phosphorylase iyadoo loo eegayo doorbidida saldhigyada nucleoside.Purine nucleoside phosphorylase waxa ay metabolize ka dhigi kartaa adenosine ilaa adenine, inosine ilaa hypoxanthine, guanosine ilaa guanine, isla markaana soo saarta fosfat ribose isku mar.Pyrimidine nucleoside phosphorylase waxay metabolizes ka dhigi kartaa uridine ilaa uracil waxayna soo saari kartaa fosfat ribose.
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Hydroaminase (HAM)
Ku saabsan Hydroaminase
Waxaa jira 2 nooc oo alaabada enzyme HAM ah (Lambarka sida ES-HAM-101 ~ ES-HAM-102) oo ay soo saartay SyncoZymes.HAM waxay kicin kartaa ammonium acid enoic ama asalkeeda si ay u soo saarto amino acids chiral.HAM waxaa loo isticmaali karaa in lagu soo saaro amino acids chiral (ama amines chiral) oo laga helo asiidhyada enoic (ama alkenes).Ku-deeqaha Ammonia, sida biyaha ammonia ama cusbada ammonium, waa lagama maarmaan.
Nooca falcelinta katalytik ee Hydroaminase
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CALB aan dhaqdhaqaaq lahayn
CALB
Dib-u-habaynta Lipase B ee Candida antarctica (CALB) waxa soo saara halsano hoostiisa oo leh Pichia pastoris oo hidde ahaan wax laga beddelay.
CALB waxaa loo isticmaali karaa marxaladda biyaha ama wejiga dabiiciga ah esterification katalytic, esterolysis, transesterification, giraanta furitaanka polyester synthesis, aminolysis, hydrolysis of amides, acylation of amines iyo falcelinta dheeraadka ah.
CALB waxay la socotaa xulasho sare oo chiral iyo xulashada booska, sidaa darteed si weyn ayaa loogu isticmaali karaa warshadaynta saliidda, cuntada, daawada, qurxinta iyo warshadaha kale ee kiimikada.
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NADH oxidase (NOX)
Ku saabsan NADH oxidase
ES-NOX (NADH oxidase): NOX waxay kicisaa oksaydhka NADH ilaa NAD+, waxayna ka tirsan tahay oxidoreductase.Habka oksaydheynta, O2 waa lagama maarmaan sida oksaydhiyaha, oo loo dhimay H2O ama H2O2.Waxaa jira 4 nooc oo ah alaabada enzyme NOX (ES-NOX-101 ~ ES-NOX-104) oo ay soo saartay shirkadeena, taas oo loo isticmaali karo dib-u-soo-nooleynta oksaydhka ee coenzyme NAD +.
Nooca falcelinta catalytic:
or
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Phenylalanine ammonia lyase (PAL)
Ku saabsan Phenylalanine ammonia lyase
ES-PAL: Waa nooc ka mid ah ensaymes kuwaas oo kicinaya deamination tooska ah ee L-phenylalanine ilaa trans-cinnamic acid.Syncozymes waxay soo saartay 10 shay oo ah phenylalanine ammonia lyase (lambarkiisu yahay ES-PAL-101~ES-PAL-110), kaas oo loo isticmaali karo deamine-ka ama falcelinta falcelinta phenylalanine iyo asalkeeda.
Nooca falcelinta catalytic:
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Catalase (CAT)
Ku saabsan Catalase
ES-CAT (Catalase): waxay kicisaa burburka H2O2 ee oksijiinta iyo biyaha.Waxay inta badan ku jirtaa mitochondria, endoplasmic reticulum, beerka xayawaanka iyo unugyada dhiigga cas, gaar ahaan beerka oo aad u badan, siinta shaqada difaaca antioxidant ee jirka.Biocatalysis, waxaa inta badan loo isticmaalaa in meesha laga saaro fal-celinta ka-soo-saarka hydrogen peroxide iyo in la dhimo ka-hortagga iyo hawlgelinta enzyme by hydrogen peroxide.Waxaa jira kaliya 1 nooc oo ah alaabada enzyme CAT ee uu sameeyay SyncoZymes (Lambarka ES-CAT).
Nooca falcelinta catalytic:
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