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Transaldolase (TAL)
Ku saabsan Transaldolase
ES-TAL (Transaldolase): inta badan waxa loola jeedaa threonine transaldolases, kaas oo kicin kara falcelinta lagu sameeyo β-hydroxyphenylalanine derivatives oo leh threonine iyo benzaldehyde derivatives. TAL waa enzyme ku tiirsan PLP. Waxaa jira 1 nooc oo keliya oo ah badeecada TAL ensaym (Lambarka ES-TAL101) oo ay samaysay SyncoZymes, kaas oo loo isticmaali karo isku-darka β-hydroxyphenylalanine iyo waxyaabaha ka soo baxa.
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Ketoreductase (KRED)
Ku saabsan Ketoreductase
Ensaymyada: Waa kiciyayaal bayooloji ah oo macromolecular ah, inta badan enzymes-ku waa borotiinno.
Ketoreductase: Sidoo kale loo yaqaan "Carbonyl reductase", waa ensaymo kiciya falcelinta redox ee la rogi karo ee u dhaxaysa aldehydes / ketones iyo alcohols, waxayna u baahan yihiin coenzymes sida gudbiyaha H sida NADH ama NADPH. Waxaa jira saddex qaybood oo waaweyn oo KRED ah: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), iyo Aldo-KetoReductases (AKRs). Hawlaha catalytic ee saddexda waa isku mid, laakiin qaab-dhismeedka iyo sifooyinka aad bay u kala duwan yihiin.
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Transaminase (ATA)
Ku saabsan transaminase
ATA oo ka socota SyncoZymes: Waxaa jira 66 nooc oo ah badeecooyinka ensaymka ATA (Lambarka sida ES-ATA-101~ES-ATA-166) oo ay samaysay SyncoZymes. SZ-ATA waa qalab waxtar leh oo lagu kicinayo isku-darka regio- iyo stereoselective ee amiinada chiral, amino acids iyo waxyaabaha ka soo baxa ee ka yimaada noocyo kala duwan oo ketoacids aliphatic iyo aromatic ah, aldehydes, ketones iyo ketoses ah.
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Nitrilase (NIT)
Ku saabsan Nitrilase
ES-NITs: Si toos ah ugu beddel kooxda cyanide kooxda carboxyl, si loo diyaariyo carboxylic acid, kaas oo si weyn loogu isticmaalo daawada, ilaalinta deegaanka, warshadaha kiimikada, waxyaabaha lagu daro cuntada, dharka, wax soo saarka beeraha iyo beeraha kale.
Waxaa jira 40 nooc oo ah alaabada Nitrilase (NIT) (Lambarka ES-NIT-101~ES-NIT-140) oo ay samaysay SyncoZymes. ES-NIT waa qalab waxtar leh oo lagu kicinayo isku-darka asiidhyada chiral carboxylic iyada oo loo marayo hydrolysis-ka gobolka iyo stereoselective ee noocyo badan oo nitriles aliphatic iyo aromatic ah.Nooca falgalka kicinta:
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Nitrile hydratase (NHT)
Ku saabsan ES-NHTs
ES-NHTs: nooc ka mid ah metalloenzyme, kaas oo si gaar ah u milma nitriles una geliya amide-ka aasaasiga ah ee u dhigma. Si weyn ayaa loogu isticmaalaa ma aha oo kaliya isku-darka amino acids, amides, carboxylic acids iyo waxyaabaha ka soo baxa, laakiin sidoo kale diyaarinta daawooyinka chiral. Waxaa jira 24 nooc oo nitrile hydratases ah oo ay samaysay SyncoZymes (Lambarka sida ES-NHT-101～ES-NHT-124).
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Amidase (AMD)
AMD oo ka socota SyncoZymes: Waxaa jira 19 nooc oo ah badeecooyinka ensaymka AMD (Lambarka ES-AMD-101~ES-AMD-119) oo ay samaysay SyncoZymes. SZ-AMD waa qalab waxtar leh oo lagu kicinayo isku-darka regio- iyo stereoselective ee asiidhyada chiral carboxylic iyo waxyaabaha ka soo baxa ee ka yimaada noocyo kala duwan oo aliphatic iyo aromatic amides ah.
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Ene reductase (ERED)
Ku saabsan ene reductase
ES-EREDs: Waxay ka tirsan yihiin qoyska ensaymyada jaalaha ah ee duugga ah kuwaas oo si xushmad leh u yareeya C=C ee iskudhisyada α, β-aan dheregsanayn oo leh kooxaha nuuga elektarooniga. Waxaa si weyn loogu isticmaalaa daraasadda waxyaabaha ka soo baxa amino acid, walxaha bayoolaji ah, daawooyinka dhexdhexaadka ah, xawaashka iyo baloogyada chiral.
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Oxynitrilases (HNL)
Ku saabsan oxynitrilases
ES-HNLs: Ensaym fasal ah oo si xushmad leh u kiciya ku darista HCN aldehydes (ketones) si loo helo alkoholka cyanide nooca R ama S, kuwaas oo si fudud loogu beddeli karo noocyo badan oo daroogo ama daawooyin ah iyada oo loo marayo habka kiimikada.
Waxaa jira 29 nooc oo ah badeecooyinka oxynitrilase (Lambarka ES-HNL-101～ES-HNL-129) oo ay samaysay SyncoZymes. SZ-HNL waa qalab waxtar leh oo loogu talagalay isku-darka (R)-cyanohydrins ama (S)-cyanohydrins oo ka yimaada noocyo kala duwan oo aldehydes udgoon, aliphatic iyo heterocyclic ah ama xitaa ketones.
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Nitro reductase (NTR)
Ku saabsan nitro reductase
ES-NTRs: Waa flavoenzymes kuwaas oo kiciya hoos u dhigista NAD(P)H-ku-tiirsanaanta kooxaha nitro ee ku jira isku-dhafka nitroaromatic iyo nitroheterocyclic una beddela hydroxylamino iyo/ama amino derivatives. Waxaa si weyn loogu isticmaalaa isku-darka dabiiciga ah ee aromatic hydroxylamine iyo aromatic amine, daaweynta burooyinka, ogaanshaha bayoolojiga iyo burburka wasakhowga deegaanka. Waxaa jira 12 nooc oo ah alaabada Nitro reductase (NTR) (Lambarka sida ES-NTR-101~ES-NTR-112) oo ay samaysay SyncoZymes.
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Aldolase (DERA)
ES-DERAs: Waxay si wax ku ool ah u kicin kartaa ku darista stereoselective ee ketones deeq-bixiyeyaasha aldehydes-ka qaataha. Intaa waxaa dheer, falcelinta waxaa lagu samayn karaa xal biyood oo pH dhexdhexaad ah iyada oo aan la isticmaalin tallaabooyin ilaalin gaar ah. Waxay ka tirsan yihiin fasalka I aldolase, kaas oo sameeya saldhigga Shiff ee habka katalytic-ga. Substrate-ku wuxuu si isku xiran ugu xiran yahay kooxda amino ee goobta firfircoon si uu u bilaabo jabka iyo sameynta xiriirka. Farqiga u dhexeeya DERAs iyo aldolases kale ayaa ah in substrate-yada ay katalysiiyaan ay yihiin aldehydes waxayna mari karaan isku-darka aldehydes ee joogtada ah.
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Cytochrome P450 monooxygenase (CYP)
Ku saabsan CYP
ES-CYPs: Nooc ka mid ah ensaymada redox oo leh mercaptan-heme oo ah xarunta firfircoon si loo kiciyo wareejinta oksijiinta. Waa oksijiin-ka-baxa ee terminal-ka waxayna u baahan yihiin heme si ay u dhaqaajiso oksijiinta.
Cytochrome P450 monooxygenase wuxuu kiciyaa oksaydhka, epoksaydhka iyo hydroxylation ee alkyl, hydroxylation iyo oksaydhka ammonia, oksaydhka sulfur, dealkylation (oxygen, sulfur, ammonia), oksaydhka dehydrogenation, deamination iyo dehalogenation.
Waxaa jira 8 nooc oo ah badeecooyinka cytochrome P450 monooxygenase (Lambarka ES-CYP-101～ES-CYP-108) oo ay samaysay SyncoZymes.Moobayl/Wechat/WhatsApp: +86-13681683526
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Oksaydh-ka khamriga (AOX)
Ku saabsan oksaydhka khamriga
ES-AOXs: Ensaymyadani waxay awood u leeyihiin inay kiciyaan oksaydhaynta alkolada dufanka leh ama aryl-alcohols si ay u sameeyaan aldehydes. Waxay isticmaalaan oksijiin molecular laakiin uma baahna cofactor dibadda lagu daray, oo hydrogen peroxide la soo saaro.
Waxaa jira 6 nooc oo ah alaabada alkohol oxidases (Lambarka ES-AOX-101~ES-AOX-106) oo ay samaysay SyncoZymes. ES-AOX101 iyo ES-AOX102 waxay doorbidaan substrates-ka alkoholka aliphatic, ES-AOX103~ ES-AOX105 waxay doorbidaan substrates-ka alkoholka udgoonka leh, ES-AOX106 waa oxidase-ka kolestaroolka. SZ-AOX waa qalab waxtar leh oo lagu kicinayo oksaydhka alkoholka dufanka leh ama alkoholka aryl si loo soo saaro aldehydes.
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