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Ketoreductase (KRED)
Ku saabsan Ketoreductase
Enzymes: Waa kicinta bayooloji ee makromolecular, inta badan enzymes waa borotiinno.
Ketoreductase: Sidoo kale loo yaqaan "Carbonyl reductase", waa ensaymes kuwaas oo kicinaya falcelinta dib-u-celinta ee u dhexeeya aldehydes / ketones iyo aalkolada, una baahan coenzymes sida gudbiyaha H sida NADH ama NADPH.Waxaa jira saddex qaybood oo waaweyn oo KRED ah: Dehydrogenase silsilad gaaban / Reductases (SDRs), silsilad dhexdhexaad ah Dehydrogenases / Reductases (MDRs), iyo Aldo-KetoReductases (AKRs).Shaqooyinka kicinta ee saddexdu waa isku mid, laakiin qaab-dhismeedka iyo astaamuhu aad bay u kala duwan yihiin.
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Transaminase (ATA)
Ku saabsan transaminase
ATA oo ka socota SyncoZymes: Waxaa jira 66 nooc oo ah alaabada enzyme ATA (Lambarka ES-ATA-101~ES-ATA-166) ee ay soo saartay SyncoZymes.SZ-ATA waa qalab faa'iido leh si loo kiciyo regio- iyo stereoselective synthesis ee amines chiral, amino acids iyo kuwa ka soo jeeda noocyo kala duwan oo aliphatic iyo ketoacids aromatic, aldehydes, ketones iyo ketoses.
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Nitrilase (NIT)
Ku saabsan Nitrilase
ES-NITs: Si toos ah ugu beddelo kooxda cyanide kooxda karboxyl, si ay u diyaariyaan karboxilic acid, taas oo si weyn loogu isticmaalo daawada, ilaalinta deegaanka, warshadaha kiimikada, cuntada lagu daro, dhar, wax soo saarka beeraha iyo beeraha kale.
Waxaa jira 40 nooc oo badeecooyin Nitrilase ah (NIT) ah (Lambarka ES-NIT-101~ES-NIT-140) oo ay soo saartay SyncoZymes.ES-NIT waa qalab faa'iido leh oo lagu kicinayo isku-darka asiidhyada karboksilic ee chiral iyada oo loo marayo regio- iyo stereoselective hydrolysis ee noocyo kala duwan oo aliphatic iyo nitriles udgoon.Nooca falcelinta catalytic:
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Nitrile hydratase (NHT)
Ku saabsan ES-NHTs
ES-NHTs: waa nooc ka mid ah metalloenzyme, kaas oo si xushmad leh u fuuqbixiya nitriles-ka u dhigma amide aasaasiga ah.Waxaa si ballaaran loo isticmaalaa ma aha oo kaliya loogu talagalay isku dhafka amino acids, amides, acids karboksylic iyo kuwa ka soo jeeda, laakiin sidoo kale diyaarinta daawooyinka chiral.Waxaa jira 24 nooc oo nitrile hydratases ah oo ay soo saartay SyncoZymes (Lambarka sida ES-NHT-101～ES-NHT-124).
Nooca falcelinta catalytic:
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Amidase (AMD)
AMD oo ka socota SyncoZymes: Waxaa jira 19 nooc oo ah alaabada enzyme AMD (Lambarka sida ES-AMD-101~ES-AMD-119) oo ay soo saartay SyncoZymes.SZ-AMD waa qalab faa'iido leh si loo kiciyo regio- iyo stereoselective synthesis ee asiidhyada karboksylic ee chiral iyo kuwa ka soo jeeda noocyo kala duwan oo aliphatic iyo amides caraf udgoon.
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Ene reductase (ERED)
Ku saabsan ene reductase
ES-EREDs: Waxay ka tirsan yihiin qoyska enzymes jaalaha ah ee hore kuwaas oo si xushmad leh u yareeya C = C ee α, β - xeryahooda aan la daboolin oo leh kooxo elektaroonig ah.Waxaa si weyn loogu isticmaalaa daraasadda soosaarayaasha amino acids, walxaha bioactive, dhexdhexaadiyeyaasha dawooyinka, dhir udgoon iyo blocks chiral.
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Oxynitrilases (HNL)
Ku saabsan oxynitrilases
ES-HNLs: Enzyme fasalka kaas oo si firfircoon u kicinaya ku darida HCN ee aldehydes (ketones) si loo helo khamriga cyanide nooca R ama S, kaas oo si fudud loogu beddeli karo noocyo badan oo daroogo ah ama dhexdhexaadin daroogo iyada oo loo marayo habka kiimikada.
Waxaa jira 29 nooc oo ah alaabada oxynitrilase (Lambarka ES-HNL-101～ES-HNL-129) oo ay soo saartay SyncoZymes.SZ-HNL waa qalab waxtar u leh regio- iyo stereo-xushay synthesis of (R) -cyanohydrins ama (S) -cyanohydrins ka noocyo kala duwan oo uduga, aliphatic iyo heterocyclic aldehyde ama xataa ketones.
Nooca falcelinta catalytic:
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Nitro reductase (NTR)
Ku saabsan nitro reductase
ES-NTRs: Waa flavoenzymes kuwaas oo kicinaya hoos u dhigista NAD (P) H-ku-tiirsanaanta ee kooxaha nitroomatic iyo nitroheterocyclic xeryahooda hydroxylamino iyo/ama soosaarayaasha amino.Waxaa si weyn loo isticmaalaa in synthesis organic of aromatic hydroxylamine iyo amine udgoon, therapy burooyinka, ogaanshaha bayooloji iyo xaalufinta wasakh deegaanka.Waxaa jira 12 nooc oo ah alaabada Nitro reductase (NTR) (Lambarka sida ES-NTR-101~ES-NTR-112) ee ay soo saartay SyncoZymes.
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Aldolase (DERA)
ES-DERAs: Waxay si wax ku ool ah u kicin kartaa isugeynta istiraatijiga ah ee ketones deeq-bixiyeyaasha ee aldehyde soo-qabtayaasha.Waxaa intaa dheer, falcelinta waxaa lagu samayn karaa xal aqueous ah pH dhexdhexaad ah iyada oo aan tallaabooyin ilaalin gaar ah.Waxay ka tirsan yihiin fasalka I aldolase, kaas oo ka dhigaya saldhigga Shiff ee habka kicinta.Substrate-ka ayaa si wadajir ah ugu xidhan kooxda amino ee goobta firfircoon si loo bilaabo jebinta iyo samaynta curaarta.Farqiga u dhexeeya DERAs iyo aldolases kale waa in substrate-yada ay kiciyaan ay yihiin aldehyde oo ay mari karaan uumi aldehydes joogto ah.
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Cytochrome P450 monooxygenase (CYP)
Ku saabsan CYP
ES-CYPs: Waa nooc ka mid ah enzymes redox oo leh mercaptan-heme oo ah xarun firfircoon si ay u kiciso wareejinta oksijiinta.Waxay yihiin oxygenases-ka-baxa waxayna u baahan yihiin heme si ay u dhaqaajiyaan ogsijiinta.
Cytochrome P450 monooxygenase katalyze oxidation, Epoxidation iyo hydroxylation of alkyl, hydroxylation iyo oxidation of ammonia, oxidation of baaruud, dealkylation (oxygen, baaruud, ammonia), fuuqbaxa oxidative, deamination iyo dehalogenation.
Waxaa jira 8 nooc oo cytochrome P450 monooxygenase ah (Lambarka ES-CYP-101-ES-CYP-108) oo ay soo saartay SyncoZymes.Mobile/Wechat/WhatsApp: +86-13681683526
iimayl:lchen@syncozymes.com
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Alcohol oxidase (AOX)
Ku saabsan alkohol oxidase
ES-AOXs: Ensaymes-yadani waxay awoodaan inay kiciyaan oksaydhka alkolada dufanka leh ama aryl-alcohols si ay u sameeyaan aldehyde.Waxay isticmaalaan ogsijiin molecular laakiin uma baahna cofactor dibadda ah oo lagu daro, iyo hydrogen peroxide ayaa la soo saaray.
Waxaa jira 6 nooc oo ah alaabada alkohol-oxidases (Lambarka sida ES-AOX-101~ES-AOX-106) oo ay soo saartay SyncoZymes.ES-AOX101 iyo ES-AOX102 waxay door bidaan substrate-ka alkolada aliphatic, ES-AOX103~ ES-AOX105 waxay door bidaan alkolada caraf udgoon, iyo ES-AOX106 waa kolestarool oxidase.SZ-AOX waa qalab faa'iido leh si loo kiciyo oksaydhka alkolada dufanka leh ama alkolada aryl si loo soo saaro aldehyde.
Nooca falcelinta catalytic:
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D-Amino acid dehydrogenase (D-AADH)
Ku saabsan D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): ensaymes oo yarayn kara 2-keto acid una dhigma D-amino acid.Dareen-celinta waxay u baahan tahay NADP (H) iyo ku-deeqaha ammonia-ga aan noolayn (sida ammonia ama ammonium ion).Waxaa jira 17 nooc oo ah D-amino acid dehydrogenases (Lambarka ES-DAADH-101~ ES-DAADH-117) oo ay soo saartay SyncoZymes.
Nooca falcelinta catalytic:
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